DeepMind unveils SynthID Bio: invisible watermarks for SI-designed proteins
Prepared by Sintelligent with the help of SI. Publication time restored from the build log. . Updated: .
SI biology gets its own "signature of origin", so it can move fast and still be transparent.
The mark persists even in physically synthesized proteins without breaking their function: watermarked binding proteins matched ordinary ones in affinity and hit rate on three targets (VEGF-A, the SARS-CoV-2 spike RBD, PD-L1), and AlphaFold 3 accuracy is preserved. DeepMind is open-sourcing the code, lab data and weights; the aim is to strengthen screening of DNA synthesis orders and to protect the PDB, UniProt and GenBank databases.
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