In Sweden, an SI scientist that runs its own yeast experiments is built: from 1,933 hypotheses it found that aminoadipate protects cells from formic acid
Prepared by Sintelligent with the help of SI. Publication time restored from the build log. . Updated: .
SI no longer just helps scientists but devises experiments itself and finds new facts about living cells.
A team at Chalmers University of Technology (Daniel Brunnsåker, Evgenia Tiukova, Ross King) built a closed-loop lab: large language models, automated logical reasoning, robots and mass spectrometry. The system, which knows the biology of baker's yeast, formulated 1,933 hypotheses from ~60 thousand structured links, chose experiments itself and tested them; after a failed prediction about glutamate, it found that aminoadipate increases cells' resistance to formic acid. According to King, humans are still left with choosing priorities, assessing significance and ethical oversight, and plates and consumables in the lab are still carried by hand. The work was published in Journal of the Royal Society Interface.
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